Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Antibodies » Abs to Multi Drug Resistance (MDR) » Anti -MDR Protein (PE) (MRP1, Multidrug resistance-associated protein 1, ABCC1, ATP-binding cassette sub-family C member 1, Leukotriene C(4) transporter)

Anti -MDR Protein (PE) (MRP1, Multidrug resistance-associated protein 1, ABCC1,
ATP-binding cassette sub-family C member 1, Leukotriene C(4) transporter)

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified B IP IH IC
MRP1 is a 190kD transmembrane phosphoglycoprotein overexpressed in various human multidrug resistant tumor cell lines and tumors (1-5).
Catalog #M2825-13C
ApplicationsSuitable for use in Western Blot, Immunoprecipitation, Flow Cytometry, Immunocytochemistry and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 1:100-1:500 (Anti mouse IgG labeled with HRP).
Immunocytochemistry: 1:20-1:50. [PBS, 0.5% paraformaldehyde-fixed or 70% methanol-fixed cytospin preparations (2)].
Immunohistochemistry: FFPE sections following antigen retrieval by microwave heating in citrate (5).
Flow Cytometry: 1:20. Cells fixed in PBS, 0.5% paraformaldehyde for 30 minutes, followed by anti-mouse IgG labeled with FITC. Note: Block and wash with solution containing 0.1% Tween.
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity. Protect from light.
Clone TypeMonoclonal
IsotypeIgG1
Clone No3H406
HostMouse
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in PBS, pH 7.2. Labeled with R-Phycoerythrin (PE).
PurityPurified by affinity chromatography.
ImmunogenNon-denatured membranes prepared from the human small cell lung cancer cell line, H69AR, which highly overexpresses MRP1(1-3).
SpecificityRecognizes human MDR protein with a defined linear epitope (aa918-924) of MRP1. Does not crossreact with human MDR1, MDR3, MRP2, MRP3, MRP4, MRP5 or MRP6 gene products. Does not crossreact with mouse mrp1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


External Links