Anti -MDR1 (Multi Drug Resistance Protein 1, ABC20, ATP Binding Cassette Subfamily B
(MDR/TAP) Member 1, ABCB1, CD243, CLCS, GP170, P-Glycoprotein, P-gp, P Glycoprotein 1,
PGY1)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
B IH FC IF |
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| The selection of cell lines exhibiting multi-drug resistance offers the opportunity to investigate the mechanism of pleiotropic drug resistance in vitro. Reportedly useful in making a distinction between drug-sensitive and drug-resistant CHO cells. | | | Catalog # | M2825-14A | | Applications | Suitable for use in Flow Cytometry, Immunofluorescence, Western Blot, and Immunohistochemistry. Other applications have not been tested. | | Recommended Dilution | Western Blot: 1-2 ug/ml for 2 hours at room temperature. | | Immunohistochemistry: acetone fixed frozen. | | Optimal dilutions to be determined by the researcher. | | Positive Control | Drug resistant Chinese Hamster Ovary (CHO) cells. | | Cellular Localization | Cell membrane | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1,k | | Clone No | 0.N.504 | | Host | Mouse | | Source | Hamster | | Concentration | ~0.1mg/ml | | Form | Supplied as a liquid in 10mM PBS, pH 7.4, with 0.2% BSA and 0.09% sodium azide. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | Colchicine-resistant viable Chinese Hamster Ovary (CHO) cells, followed by purified P170 glycoprotein from CHO cells. | | Specificity | Recognizes a membrane glycoprotein of 170kD in drug-resistant chinese hamster ovary (CHO) cells, which is identified as multi-drug resistance(MDR) associated p-glycoprotein (p170). Does not react with human. Shows no crossreactivity with parent drug-sensitive CHO cells. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -MDR1 (Multi Drug Resistance Protein 1, ABC20, ATP Binding Cassette Subfamily B (MDR/TAP) Member 1, ABCB1, CD243, CLCS, GP170, P-Glycoprotein, P-gp, P Glycoprotein 1, PGY1) |
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