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You are here:Home » Antibodies » Abs to Multi Drug Resistance (MDR) » Anti -MDR1 (Multi Drug Resistance Protein 1, Multidrug Resistance Protein 1, ABC20, ATP Binding Cassette Subfamily B (MDR/TAP) Member 1, ABCB1, CD243, CLCS, GP170, MGC163296, P-Glycoprotein, P-gp, P Glycoprotein 1, PGY1)

Anti -MDR1 (Multi Drug Resistance Protein 1, Multidrug Resistance Protein 1, ABC20, ATP
Binding Cassette Subfamily B (MDR/TAP) Member 1, ABCB1, CD243, CLCS, GP170, MGC163296,
P-Glycoprotein, P-gp, P Glycoprotein 1, PGY1)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified B IH
P Glycoprotein belongs to the MDR/TAP subfamily of ATP-binding cassette (ABC) transporters. P Glycoprotein is an ATP-dependent drug efflux pump expressed in liver, kidney, small intestine and brain. It is responsible for decreased drug accumulation in multidrug-resistant cells. Genetic variation in P Glycoprotein is thought to play a role in patients who do not respond to drug treatment. P Glycoprotein also functions as a transporter in the blood-brain barrier.
Catalog #M2825-14M
Applications
Suitable for use in Western Blot and Immunohisochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 0.5-1ug/ml
Immunohistochemistry (Paraffin and Formalin): 1-2ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG
Clone No10g49
HostMouse
SourceHuman
ConcentrationNot determined.
FormSupplied as a lyophilized powder from 1.2% sodium acetate, 2% BSA, 0.2% sodium azide. Reconstitute with 1ml of PBS.
PurityPurified by affinity chromatography.
ImmunogenHuman and hamster drug-resistant whole cells and crude plasma membranes.
SpecificityRecognizes human P Glycoprotein at 141kD.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesATP-binding Cassette Sub-family B Member 1, EC=3.6.3.44


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