Anti -MDR1 (Multi Drug Resistance Protein 1, Multidrug Resistance Protein 1, ABC20, ATP
Binding Cassette Subfamily B (MDR/TAP) Member 1, ABCB1, CD243, CLCS, GP170, MGC163296,
P-Glycoprotein, P-gp, P Glycoprotein 1, PGY1)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
B IH |
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| P Glycoprotein belongs to the MDR/TAP subfamily of ATP-binding cassette (ABC) transporters. P Glycoprotein is an ATP-dependent drug efflux pump expressed in liver, kidney, small intestine and brain. It is responsible for decreased drug accumulation in multidrug-resistant cells. Genetic variation in P Glycoprotein is thought to play a role in patients who do not respond to drug treatment. P Glycoprotein also functions as a transporter in the blood-brain barrier. | | | Catalog # | M2825-14M | | Applications | | | Suitable for use in Western Blot and Immunohisochemistry. Other applications not tested. | | Recommended Dilution | Western Blot: 0.5-1ug/ml | | Immunohistochemistry (Paraffin and Formalin): 1-2ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG | | Clone No | 10g49 | | Host | Mouse | | Source | Human | | Concentration | Not determined. | | Form | Supplied as a lyophilized powder from 1.2% sodium acetate, 2% BSA, 0.2% sodium azide. Reconstitute with 1ml of PBS. | | Purity | Purified by affinity chromatography. | | Immunogen | Human and hamster drug-resistant whole cells and crude plasma membranes. | | Specificity | Recognizes human P Glycoprotein at 141kD. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | ATP-binding Cassette Sub-family B Member 1, EC=3.6.3.44 |
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Download Specifications for Anti -MDR1 (Multi Drug Resistance Protein 1, Multidrug Resistance Protein 1, ABC20, ATP Binding Cassette Subfamily B (MDR/TAP) Member 1, ABCB1, CD243, CLCS, GP170, MGC163296, P-Glycoprotein, P-gp, P Glycoprotein 1, PGY1) |
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