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You are here:Home » Antibodies » Abs to Multi Drug Resistance (MDR) » Anti -MDR3 P-glycoprotein (Multidrug Resistance Protein 3, ABC21, ATP-binding Cassette Sub-family B (MDR/TAP) Member 4, ABCB4, GBD1, PFIC-3, P-glycoprotein 3, PGY3)

Anti -MDR3 P-glycoprotein (Multidrug Resistance Protein 3, ABC21, ATP-binding Cassette
Sub-family B (MDR/TAP) Member 4, ABCB4, GBD1, PFIC-3, P-glycoprotein 3, PGY3)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Supernatant B IH IC FC
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a full transporter and member of the p-glycoprotein family of membrane proteins with phosphatidylcholine as its substrate. The function of this protein has not yet been determined; however, it may involve transport of phospholipids from liver hepatocytes into bile. Alternative splicing of this gene results in several products of undetermined function.
Catalog #M2825-18R
ApplicationsSuitable for use in Immunocytochemistry, Immunohistochemistry, Western Blot and Flow Cytometry. Other applications not tested.
Recommended DilutionImmunocytochemistry: 1:20-1:50 on acetone fixed cytospin preparations.
Immunohistochemistry: 1:20 on acetone fixed frozen sections. Does not work well on formaldehyde-fixed paraffin-embedded human tissues.
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2b
Clone NoP3II-26
HostMouse
ConcentrationNot determined
FormSupplied as a liquid in 0.7% BSA, 0.1% sodium azide.
PuritySupernatant
ImmunogenFusion protein consisting of a fragment of MDR3 P-glycoprotein corresponding to aa629-692.
SpecificityRecognizes an internal epitope of MDR3 P-glycoprotein. Does not crossreact with human MDR1 P-glycoprotein.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesEC=3.6.3.44, MDR2


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