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You are here:Home » Antibodies » Abs to Transcription Factors, Homeobox (HOX) » Anti -MEIS1 (Homeobox Protein Meis1)

Anti -MEIS1 (Homeobox Protein Meis1)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified IH
MEIS1, also known as Homeobox protein Meis1, is a nuclear protein belonging to the TALE/MEIS homeobox family with a homeobox DNA-binding domain. It acts as a transcriptional regulator of PAX6 (Paired box protein Pax-6). It is a protein required for hematopoiesis, megakaryocyte lineage development and vascular patterning. Expression is seen at low levels in normal immunohepatopoietic tissues, and in a subset of myeloid leukemia cell lines, with the highest expression seen in those with a megakaryocytic-erythroid phenotype. It is also expressed at high levels in the cerebellum.
Catalog #M2862-08B
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (formalin fixed paraffin embedded): 5ug/ml
Optimal dilutions to be determined by the researcher.
Positive ControlTestis
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to aa280-330 of MEIS1.
SpecificityRecognizes MEIS1. Species Crossreactivity: chicken, human, canine, equine, mouse, rat, xenopus.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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