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You are here:Home » Antibodies » Antibodies-Transcription Factors, Zinc (Ring) Finger » Anti -Mel18 (RNF110, DNA-binding protein Mel-18, RING finger protein 110, Zinc finger protein 144, polycomb group ring finger 2)

Anti -Mel18 (RNF110, DNA-binding protein Mel-18, RING finger protein 110, Zinc finger
protein 144, polycomb group ring finger 2)


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Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
Polycomb group ring finger 2, also known as PCGF2, is a transcriptional repressor. Polycomb group (PcG) of genes were first identified in Drosophila whereby these genes were required to sustain the stable repression of Hox cluster genes during development. Studies have shown that PCGF2 forms multimeric protein complexes associated with chromatin. In addition, PCGF2 may play a role in cell proliferation and/or neural cell development. PCGF2 is widely expressed in placenta, lung, and kidneys but expressed very little in skeletal muscle, liver, and pancreas.
Catalog #M2867-60B
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1ug/ml
Optimal dilutions to be determined by the researcher.
Positive ControlHuman lung tissue lysate
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
FormSupplied as a liquid in 0.1M Tris-glycine, pH 7.4, 150mM sodium chloride, 0.05% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenLinear peptide corresponding to human RNF110/PCGF2 (KLH).
SpecificityRecognizes human RNF110/PCGF2. Species Crossreactivity
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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