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You are here:Home » Antibodies » Abs to Tyrosine Kinases » Anti -MerTK (c-MER, c-Mer Proto-oncogene Tyrosine Kinase, MER, MER Receptor Tyrosine Kinase, MERK, MERPEN, MGC133349, Proto-oncogene Tyrosine Protein Kinase MER, Receptor Tyrosine Kinase MerTK, STK Kinase)

Anti -MerTK (c-MER, c-Mer Proto-oncogene Tyrosine Kinase, MER, MER Receptor Tyrosine
Kinase, MERK, MERPEN, MGC133349, Proto-oncogene Tyrosine Protein Kinase MER, Receptor
Tyrosine Kinase MerTK, STK Kinase)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Rabbit Supernatant B IP IH FC IF
MerTK (c-mer, Nyk, Eyk) is a tyrosine kinase that belongs to a family of transmembrane receptors. MerTk has been implicated in reversible cell growth arrest, survival, proliferation and cell adhesion. Growth arrest specific protein 6 (Gas6) is an activating ligand for MerTK. MerTK is required for clearance of apoptotic cells by mononuclear phagocytes in mice; with its absence resulting in progressive lupus like autoimmunity. Defects in MERTK are a cause of retinitis pigmentosa (RP).
Catalog #M2995-01A
ApplicationsSuitable for use in Flow Cytometry, Western Blot Immunoprecipitation, Immunofluorescence and Immunohistochemistry. Other applications not tested.
Recommended DilutionsFlow Cytometry: 1:40-1:50 using paraformaldehyde or methanol fixed cells
Western Blot: 1:500
Immunohistochemistry (Paraffin): 1:50
Immunoprecipitation: 1:50
Optimal dilutions to be determined by the researcher.
Positive ControlHEK293 cell membrane lysate, human lymphoma tissue
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap
Manufactured incorporating RabMAb® technology under Epitomics US patents, No 5,675,063 and 7,429,487, owned by Abcam.
Clone TypeMonoclonal
IsotypeIgG
Clone No9H468
HostRabbit
SourceHuman
ConcentrationNot Determined
FormSupplied as a liquid in PBS, pH 7.4, 0.05% BSA, 0.01% sodium azide, 50% glycerol
PuritySupernatant
ImmunogenSynthetic peptide corresponding to residues near the N-terminal of human MerTk. Cellular Localization: Membrane
SpecificityRecognizes human MerTK at ~180kD. Does not crossreact with mouse or rat
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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