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You are here:Home » Antibodies » Abs to Enzymes, Racemase » Anti -a-Methylacyl CoA Racemase (Alpha Methylacyl CoA Racemase, Alpha Methylacyl Coenzyme A Racemase, AMACR, 2-Arylpropionyl CoA Epimerase, 2-Methylacyl CoA Racemase, EC 5.1.99.4, Macr1, Methylacyl CoA Racemase alpha, P504S, RACE)

Anti -a-Methylacyl CoA Racemase (Alpha Methylacyl CoA Racemase, Alpha Methylacyl Coenzyme
A Racemase, AMACR, 2-Arylpropionyl CoA Epimerase, 2-Methylacyl CoA Racemase, EC 5.1.99.4,
Macr1, Methylacyl CoA Racemase alpha, P504S, RACE)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified IH
Catalog #M3390-01D
P504S / AMACR / a-Methylacyl-CoA Racemase is an essential 42kD enzyme in the b-oxidation of branched-chain fatty acids. High expression of P504S protein is found in prostatic adenocarcinoma but not in benign prostate tissue by immunohistochemical staining in paraffin-embedded tissue. The expression of P504S is also detected in two premalignant lesions of the prostate high-grade prostatic intraepithelial neoplasia (PIN) and atypical adenomatous hyperplasia.
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (Formalin fixed paraffin embedded): 1:100 for 10min at RT
Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10min followed by cooling at RT for 20min
Optimal dilutions to be determined by the researcher.
Positive ControlProstate carcinoma
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostRabbit
SourceHuman
Concentration~0.1mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 0.2% BSA, 0.05% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenRecombinant corresponding to human p504s.
SpecificityRecognizes human p504s.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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