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You are here:Home » Antibodies » Abs to Enzymes, Methyltransferase » Anti -MGMT, CT (O-6-Methylguanine DNA Methyltransferase, 6-O-Methylguanine DNA Methyltransferase, Methylated DNA Protein Cysteine Methyltransferase, Methylguanine DNA Methyltransferase, O-6-Methylguanine DNA Alkyltransferase)

Anti -MGMT, CT (O-6-Methylguanine DNA Methyltransferase, 6-O-Methylguanine DNA
Methyltransferase, Methylated DNA Protein Cysteine Methyltransferase, Methylguanine DNA
Methyltransferase, O-6-Methylguanine DNA Alkyltransferase)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Purified E B IH
Catalog #M3884-90C
MGMT is involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. This protein repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the protein is irreversibly inactivated.
ApplicationsSuitable for use in ELISA, Western Blot, and Immunohistochemistry. Other applications not tested.
Recommended DilutionELISA: 1:1,000
Western Blot: 1:50-1:100
Immunohistochemistry: 1:50-1:100
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, 0.09% sodium azide.
PurityPurified by ammonium sulfate precipitation.
ImmunogenSynthetic peptide selected from the C-terminal region of human MGMT (KLH).
SpecificityRecognizes human MGMT.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesEC=2.1.1.63


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