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You are here:Home » Antibodies » Abs to MHC » Anti -MHC Class 1 (MHC Class I)

Anti -MHC Class 1 (MHC Class I)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E IH FC
Human MHC Class I (HLA-A, B & C) molecules are expressed on nearly all nucleated cells. MHC Class I molecules consist of heterodimers of a highly polymorphic transmembrane chain and an invariant chain. MHC Class I molecules bind to endogenously synthesized peptides of about 8-10aa which are presented to CD8+ T cells. Recent evidence now indicates exogenously derived peptides are also presented by MHC Class I molecules.
Catalog #M3885-48D1
ApplicationsSuitable for use in ELISA, Flow Cytometry and Immunohistochemistry. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2a
Clone No7H121
HostMouse
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in 50mM sodium phosphate, pH 7.5, 100mM potassium chloride, 150mM sodium chloride.
PurityPurified by Protein A affinity chromatography.
ImmunogenHuman HSB-2 T cell line
SpecificityRecognizes human MHC Class I. Recognizes a monomorphic Class I epitope on the chain.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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