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You are here:Home » Antibodies » Abs to MHC » Anti -MHC Class 1 (PE)

Anti -MHC Class 1 (PE)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified FC
Human MHC Class I (HLA-A, B & C) molecules are expressed on nearly all nucleated cells. MHC Class I molecules consist of heterodimers of a highly polymorphic transmembrane a chain and an invariant b chain. MHC Class I molecules bind to endogenously synthesized peptides of about 8-10 amino acids which are presented to CD8+ T cells. Recent evidence now indicates exogenously derived peptides are also presented by MHC Class I molecules.
Catalog #M3885-48G
ApplicationsSuitable for use in Flow Cytometry. Other applications not tested.
Recommended Dilution; Flow Cytometry 1:50 (or use 1.6ul concentrated stock per 5x10e5 cells per test)
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only pror to immediate use. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity.
Clone TypeMonoclonal
IsotypeIgG2a
Clone No7H121
HostMouse
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS containing 15% glycerol, 0.2% BSA, and 0.04% sodium azide. Labeled with R-Phycoerythrin.
PurityPurified by Protein A affinity chromatography.
ImmunogenHuman HSB-2 T cell line
SpecificityRecognizes human MCH Class I (HLA-A, B and C) molecules. Recoognizes a monomorphic Class I epitope on the alpha chain.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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