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You are here:Home » Antibodies » Abs to MHC » Anti -MHC Class 1 HLA ABC

Anti -MHC Class 1 HLA ABC

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified FC
Human MHC class I antigens are expressed constitutively on all nucleated cells such as lymphocytes, thymocytes, granulocytes and bone marrow cells and are absent on erythrocytes. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance and tissue allotransplantation. This clone also reacts strongly with primate cells.
Catalog #M3886-10
ApplicationsSuitable for use in Flow Cytometry. Other applications not tested.
Recommended DilutionsOptimal dilutions to be determined by the researcher.
Positive ControlHuman lymphocytes, Tonsil and lymph nodes
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. 
Clone TypeMonoclonal
IsotypeIgG2a,k
Clone No0.N.414
HostMouse
SourceHuman
Concentration~0.2mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 0.2% BSA, 0.09% sodium azide. Also available without BSA and azide. See M3886-10X.
PurityPurified by Protein A affinity chromatography.
ImmunogenHuman peripheral blood leukocytes. Cellular Localization: Cell membrane.
SpecificityRecognizes a monomorphic determinant of human major histocompatibility (MHC) class I antigens (HLA-A, B and C).
Species CrossreactivityPrimates
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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