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You are here:Home » Antibodies » Abs to MHC » Anti -MHC Class 1 Chain-related Gene A, B (MHC Class 1 Chain-related Gene A, MHC Class I Polypeptide-related Sequence A, MICA, MIC-A, MHC Class 1 Chain-related Gene B, MHC Class I Polypeptide-related Sequence B, MICB, MIC-B, PERB11.1, PERB11.2) (FITC)

Anti -MHC Class 1 Chain-related Gene A, B (MHC Class 1 Chain-related Gene A, MHC Class I
Polypeptide-related Sequence A, MICA, MIC-A, MHC Class 1 Chain-related Gene B, MHC Class I
Polypeptide-related Sequence B, MICB, MIC-B, PERB11.1, PERB11.2) (FITC)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified FC
MHC Class 1 Chain-related Gene A, B (MICA, MICB) are stress inducible antigens, which are closely related and appear functionally indistinguishable. MICA and MICB are ligands for NKG2D, an activating receptor on most natural killer (NK) cells, CD8 T cells and gamma delta T cells. MICA is principally expressed on intestinal epithelium, and several epithelial tumours. Expression may be induced to high surface levels by heat shock, oxidative stress, and virus infection.
Catalog #M3886-75Y3
ApplicationsSuitable for use in Flow Cytometry. Other applications not tested.
Recommended DilutionsFlow Cytometry: Neat; 10ul labels 10e6 cells in 100ul. Requires membrane permeabilization.
Optimal dilutions to be determined by the researcher.
HybridomaSpleen cells from immunized RBF/DnJ mice were fused with cells of the P3 myeloma cell line.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. FITC conjugates are sensitive to light.
Clone TypeMonoclonal
IsotypeIgG2a
Clone No10F158
HostMouse
SourceHuman
Concentration~0.1mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 1% BSA, 0.09% sodium azide. Labeled with fluorescein isothiocyanate (FITC).
PurityPurified by Protein G affinity chromatography.
ImmunogenMICA transfected C1R cells
SpecificityRecognizes human nonclassical MHC Class 1 Chain A (MICA) and nonclassical MHC class I chain MICB (MICB).
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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