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You are here:Home » Antibodies » Abs to MHC » Anti -MHC Class 2 (DMA, DMB, DP beta 1, DPB1, DRB, HLA Class II Histocompatibility Antigen DM beta Chain, HLA DMB, HLADM, HLADPB1, Major Histocompatibility Complex Class II (DP beta 1), MHC Class II Antigen DMB, MHC DPB1, RING6, RING7)

Anti -MHC Class 2 (DMA, DMB, DP beta 1, DPB1, DRB, HLA Class II Histocompatibility Antigen
DM beta Chain, HLA DMB, HLADM, HLADPB1, Major Histocompatibility Complex Class II (DP beta
1), MHC Class II Antigen DMB, MHC DPB1, RING6, RING7)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified B IH FC IF
MHC Class II antigen is involved in the antigen presentation by APCs for CD4+ T cells. It is constitutively expressed on APCs including B cells, macrophages, monocytes and dendritic cells, and is inducible on a number of other cells (endothelium and epithelial cells) by interferon gamma.
Catalog #M3887-10H
Cellular Localization Type I membrane protein. Localizes to late endocytic compartment. Associates with lysosome membranes.
ApplicationsSuitable for use in Immunofluorescence, Flow Cytometry, Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50%glycerol, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1,k
Clone No8L765
HostMouse
SourceRat
Concentration~2mg/ml
FormSupplied as a liquid in PBS, pH 7.2.
PurityPurified by Protein A affinity chromatography.
ImmunogenPurified full length native protein (Rat).
SpecificityReacts with monomorphic determinant on beta chain of RT-1B molecules. Does not crossreact with RT-1A,-C,-D rat MHC products. Species Crossreactivity: Crossreacts with Rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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