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You are here:Home » Antibodies » Abs to MHC » Anti -MHC Class 2, D, DP (DMA, DMB, DP beta 1, DPB1, DRB, HLA Class II Histocompatibility Antigen DM beta Chain, HLA DMB, HLADM, HLADPB1, Major Histocompatibility Complex Class II (DP beta 1), MHC Class II Antigen DMB, MHC DPB1, RING6, RING7)

Anti -MHC Class 2, D, DP (DMA, DMB, DP beta 1, DPB1, DRB, HLA Class II Histocompatibility
Antigen DM beta Chain, HLA DMB, HLADM, HLADPB1, Major Histocompatibility Complex Class II
(DP beta 1), MHC Class II Antigen DMB, MHC DPB1, RING6, RING7)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified IP FC
Human MHC class II antigens are transmembrane glycoproteins composed of an á chain (36kD) and a beta chain (27kD). They are expressed primarily on antigen presenting cells. Human MHC class II genes are located in the HLA-D region that encodes at least six á and ten beta chain genes. Three loci, DR, DQ and DP, encode the major products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells. They therefore have a critical role in the initiation of the immune response. It has been shown that some autoimmune diseases are associated with certain class II alleles.
Catalog #M3887-10K
ApplicationsSuitable for use in Flow Cytometry and Immunoprecipitation. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG2a
Clone No9L391
HostMouse
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.4, 15mM sodium azide
PurityPurified by Protein A affinity chromatography.
ImmunogenBurkitt’s lymphoma cell line Raji.
SpecificityRecognizes a common epitope on the beta-chain of HLA-DR and HLA-DP. Species crossreactivity: human, pig.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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