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Anti -MHC Class 2, DQ alpha, Monomorphic (MHC Class II)
Anti -MHC Class 2, DQ alpha, Monomorphic (MHC Class II)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Supernatant |
E B IP IH FC |
|
| The major histocompatibility complex (MHC) is a cluster of genes some of which are important in the immune response to infections. In sheep, this complex is referred to as the ovine leukocyte antigen (OLA) region. There are 2 major types of MHC class IIa molecules encoded by the OLA which are DR and DQ each composed of an alpha and beta chain. | | | Catalog # | M3887-40 | | Applications | Suitable for use in ELISA, Flow Cytometry, Immunohistochemistry, Western Blot and Immunoprecipitation. Other applications not tested. | | Recommended Dilutions | Immunohistochemistry: Frozen sections | | Immunohistochemistry (paraffin): Does not require protein digestion pre-treatment of paraffin sections. Does not require antigen retrieval using heat treatment prior to staining paraffin sections. | | Western Blot: Reported as suitable | | Optimal dilutions to be determined by the researcher. | | Hybridoma | NSO myeloma cells with spleen cells from Balb/c mice. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 10F110 | | Host | Mouse | | Source | Sheep | | Concentration | Not Determined | | Form | Supplied as a liquid in 0.2M Tris-HCl, pH 7.4, 5-10% fetal calf serum, 0.01% sodium azide. | | Purity | Supernatant | | Immunogen | Acid treated ovine MHC Class II | | Specificity | Recognizes a monomorphic epitope on the alpha chain of sheep MHC class II DQ molecules which are constitutively expressed on antigen presenting cells such as dendritic cells, B lymphocytes, monocytes, macrophages, activated T lymphocytes and may be induced on a range of other cell types by interferon gamma. Species Crossreactivity: bovine | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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