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You are here:Home » Antibodies » Abs to MHC » Anti -MHC Class 2, I-A/I-E (H-2 Class II Histocompatibility Antigen, E-D alpha Chain, H2-IE-alpha, H2-Ea/H-2 Class II HA, I-A beta Chain, H2-Eb1)

Anti -MHC Class 2, I-A/I-E (H-2 Class II Histocompatibility Antigen, E-D alpha Chain,
H2-IE-alpha, H2-Ea/H-2 Class II HA, I-A beta Chain, H2-Eb1)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Rat Affinity Purified FC
MHC Class 2, I-A/I-E reacts with a polymorphic determinant shared by the I-Ab, I-Ad, I-Aq, I-Ed, and I-Ek MHC class II alloantigens. These class II molecules are expressed on antigen presenting cells (including B cells) and a subset of T cells from H-2b,d,q,r bearing mice and are involved in antigen presentation to T cells expressing CD3/TCR and CD4 proteins. M3887-48G cross-reacts with the H-2p,r haplotypes. This antibody has been reported to block antigen presentation.
Catalog #M3887-48G
ApplicationsSuitable for use in Flow Cytometry. Other applications not tested.
Recommended DilutionFlow Cytometry: 0.5ug/10e6 cells in 100ul volume
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2b,k
Clone NoM5/114.15.2
HostRat
SourceMouse
Concentration~0.1mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenActivated C57BL/6 mouse spleen cells
SpecificityRecognizes mouse a polymorphic determinant shared by the I-Ab, I-Ad, I-Aq, I-Ed, and I-Ek MHC class II alloantigens. Crossreactivity: H-2p,r haplotypes.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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