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You are here:Home » Antibodies » Abs to MHC » Anti -MHC Class I (RT1A)

Anti -MHC Class I (RT1A)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B IH FC
Soluble MHC class I antigens can be detected in the serum of humans and various animals and appear in the circulation shortly after liver transplantation. The precise role of these antigens is currently uncertain, but soluble MHC class I may be involved in immunomodulation. MHC class I is a dimmer composed of two polypeptide chains, an a chain (44kD) and a non-covalently associated protein, b2 microglobulin (12kD).
Catalog #M3887-49P
ApplicationsSuitable for use in Flow Cytometry, ELISA, Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionsImmunohistochemistry: Frozen sections
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2a
Clone No9F631
HostMouse
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, pH 7.2.
PurityPurified by Protein G affinity chromatography.
ImmunogenHuman tonsil leukocyte membrane preparation
SpecificityRecognizes human Major Histocompatibility Complex class I. Reacts with a monomorphic epitope on the alpha chain polypeptide of human class I HLA molecules (HLA-A, B, C).
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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