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You are here:Home » Antibodies » Abs to MHC » Anti -MHC Class I (H-2 class I histocompatibility antigen, K-B alpha chain precursor, H-2 Class I histocompatibility antigen, K-D alpha chain precursor, H-2 class I histocompatibility antigen, K-K alpha chain precursor, H-2 class I histocompatibility antigen, K

Anti -MHC Class I (H-2 class I histocompatibility antigen, K-B alpha chain precursor, H-2
Class I histocompatibility antigen, K-D alpha chain precursor, H-2 class I
histocompatibility antigen, K-K alpha chain precursor, H-2 class I histocompatibility
antigen, K

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Rat Affinity Purified IH FC
The primary immunological function of MHC molecules is to bind and present antigenic peptides on the surfaces of cells for recognition by the antigen-specific T cell receptors (TCRs) of lymphocytes. MHC class I molecules are expressed on the surfaces of most cells and are recognized by CD8-positive cytotoxic T-cells, an essential step for initiating the elimination of virally infected cells by T-cell-mediated lysis. MHC class I molecules are heterodimers composed of an alpha (44kD) and a beta (beta microglobulin, 11kD) subunit. The first two structural domains of the alpha subunit associate to form the peptide-binding pocket.
Catalog #M3887-49Q
ApplicationsSuitable for use in Flow Cytometry and Immunohistochemistry.
Other applications not tested.
Recommended DilutionsFlow Cytometry: 1:50
Immunohistochemistry (frozen): 1:50
The antigen is glutaraldehyde (0.05%) and paraformaldehyde (1%) resistant.
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap
Clone TypeMonoclonal
IsotypeIgG2a
Clone No9G232
HostRat
SourceMouse
Concentration~0.1mg/ml
FormSupplied as a liquid in PBS, 0.1% BSA, 0.02% sodium azide.
PurityPurified by Protein G affinity chromatography.
SpecificityRecognizes mouse (MHC) class. It recognizes murine MHC class I molecules on the surface of cells of the following haplotypes
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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