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You are here:Home » Antibodies » Abs to MHC » Anti -MHC Class 2, I-Ak (H-2 Class II Histocompatibility Antigen, A-K alpha Chain, H2-Aa, H-2 Class II Histocompatibility Antigen, A-K beta Chain, H2-Ab1)

Anti -MHC Class 2, I-Ak (H-2 Class II Histocompatibility Antigen, A-K alpha Chain, H2-Aa,
H-2 Class II Histocompatibility Antigen, A-K beta Chain, H2-Ab1)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified IP IH FC
This antibody reacts with the alpha chain of the I-Ak MHC class II alloantigen. These class II molecules are expressed on antigen presenting cells (including B cells) and a subset of T cells from H-2k bearing mice and are involved in antigen presentation to T cells expressing CD3/TCR and CD4 proteins. This antibody cross-reacts with cells from mice bearing the H-2r haplotype. Reactivity with other H-2 haplotypes (e.g., b, d, f, p, q, s) has not been observed. This antibody has been reported to block antigen presentation and induce B cell differentiation.
Catalog #M3887-53D
ApplicationsSuitable for use in Flow Cytometry, Immunohistochemistry and Immunoprecipitation. Other applications not tested.
Recommended DilutionFlow Cytometry: 1ug/10e6 cells in 100ul volume
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2b,k
HostMouse
SourceMouse
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenCKB mouse splenocytes
SpecificityRecognizes mouse k haplotype, Crossreactivity: H-2r haplotypes. Does not cross react with other haplotypes. (e.g., b, d, f, p, q, s).
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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