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You are here:Home » Antibodies » Abs to MHC » Anti -MHC Class 2, beta Chain (MHC Class II)

Anti -MHC Class 2, beta Chain (MHC Class II)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified B IH FC
Human MHC Class II (HLA-DP, DQ & DR) molecules are expressed on dendritic cells, monocytes, macrophages, and myeloid cells. MHC Class II molecules are heterodimers of polymorphic transmembrane and chains and generally bind exogenously derived peptides of about 10-17aa. MHC Class II molecules interact with the T cell receptor on CD4+ T cells.
Catalog #M3887-55A2
ApplicationsSuitable for use in Western Blot, Flow Cytometry and Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (Formalin fixed paraffin embedded): 10ug/ml
Immunohistochemistry: Frozen
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone NoTDR31.1
HostMouse
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in 50mM sodium phosphate, pH 7.5, 100mM potassium chloride, 150mM sodium chloride, 0.5mg/ml Gentamicin sulfate.
PurityPurified by Protein A affinity chromatography.
ImmunogenPurified class II from JY cell line
SpecificityRecognizes human Monomorphic class II beta chain epitope.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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