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Migration Inhibitory Factor, Macrophage, Recombinant, Human (Macrophage MIF, Glycosylation-Inhibiting Factor, GIF, GLIF, MMIF)
Migration Inhibitory Factor, Macrophage, Recombinant, Human (Macrophage MIF,
Glycosylation-Inhibiting Factor, GIF, GLIF, MMIF)
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| The cytokine Macrophage migration inhibitory factor (MIF) has been identified to be secreted by the pituitary gland and the monocyte/macrophage and to play an important role in endotoxic shock. MIF has the unique property of being released from macrophages and T cells in response to physiological concentrations of glucocorticoids. The secretion of MIF is tightly regulated and decreases at high, anti-inflammatory steroid concentration. | | | Catalog # | M3895-07L | | Source | Recombinant corresponding to aa1-115 of human Macrophage MIF expressed in | | E. coli (NP_002406). | | Sequence MPMFIVNTNV PRASVPDGFL SELTQQLAQA TGKPPQYIAV HVVPDQLMAF GGSSEPCALC SLHSIGKIGG AQNRSYSKLL CGLLAERLRI SPDRVYINYY DMNAANVGWN NSTFA | | Molecular Weight | 12kD (115 aa) | | Applications | Suitable for use in Western Blot. Other applications not tested. | | Recommended Dilution | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | Molecular Weight | 12kD | | Source | E .coli. | | Purity | ~98% by SDS PAGE. | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in 50mM Tris-HCl, pH 8.0, 0.5mM DTT, 10% glycerol. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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