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You are here:Home » Biochemicals » Biochem-Antibiotics » Mitoxantrone (1,4-Dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-9,10-anthracenedione)



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An anti-tumor antibiotic and type II topoisomerase inhibitor. It disrupts DNA synthesis and DNA repair in both healthy and cancer cells. Mitoxantrone also displays broad immunosuppressive activity inhibiting proliferation of all classes of lymphocytes and inducing apoptosis of antigen-presenting T cells.
Catalog #M4017-01
Molecular Weight~444.48
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Protect from heat and light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
CAS Number65271-80-9
Molecular FormulaC H N O
Molecular Weight444.48
PurityHighly Purified (~98%)
FormSupplied as a dark blue solid.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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