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M4141-01B Goat Anti-MLX (Max-like protein X, Transcription factor-like protein 4)

Specifications
References
Clone Type
Polyclonal
Host
Goat
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E
Crossreactivity
Hu
Accession #
NP_937848.1; NP_937847.1; NP_733752.1
Shipping Temp
Blue Ice
Storage Temp
-20°C
transcription factor-like protein 4, transcription factor-like 4, MAX-like bHLHZIP protein, BigMax protein, bHLHd13, TCFL4, MXD7, MAD7, MAX-like protein X, MLX

The product of this gene belongs to the family of basic helix-loop-helix leucine zipper (bHLH-Zip) transcription factors. These factors form heterodimers with Mad proteins and play a role in proliferation, determination and differentiation. This gene product may act to diversify Mad family function by its restricted association with a subset of the Mad family of transcriptional repressors, namely, Mad1 and Mad4. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Applications
Suitable for use in ELISA. Other applications have not been tested.
Recommended Dilutions
Peptide ELISA Titer: 1:128,000 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Synthetic peptide corresponding to C-QIVKAHQDNPHEGED, from the internal region of human MLX (NP_937848.1; NP_937847.1; NP_733752.1).
Form
Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Purity
Purified by peptide affinity chromatography.
Specificity
Recognizes MLX. Species sequence homology: human, mouse, rat, canine, bovine. This antibody is expected to recognize all three reported isoforms (NP_937848.1; NP_937847.1; NP_733752.1).
References
1. Stoltzman CA, Peterson CW, Breen KT, Muoio DM, Billin AN, Ayer DE, Glucose sensing by MondoA:Mlx complexes: a role for hexokinases and direct regulation of thioredoxin-interacting protein expression. Proceedings of the National Academy of Sciences of the United States of America 2008 May 105 (19): 6912-7.
USBio References
No references available
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