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You are here:Home » Antibodies » Abs to Monocarboxylate Transporter » Anti -MCT2 (Monocarboxylate Transporter 2, MCT 2, Solute Carrier Family 16 Member 7, SLC16A7)

Anti -MCT2 (Monocarboxylate Transporter 2, MCT 2, Solute Carrier Family 16 Member 7,
SLC16A7)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
Lactic acid and pyruvate transport across plasma membranes is catalyzed by members of the proton-linked monocarboxylate transporter (MCT) family, which has been designated solute carrier family 16. Each MCT appears to have slightly different substrate and inhibitor specificities and transport kinetics, which are related to the metabolic requirements of the tissues in which it is found. MCT2 is a high affinity transporter that catalyzes the rapid transport of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate across the plasma membrane.
Catalog #M4470-12C
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:128,000
Western Blot: 1-3ug/ml, observed in A549, lung epithelial (lung carcinoma) lysates on ~40-45kD bands
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to C-SNAQSVTSERETNI, from human SLC16A7, at C-terminal (NP_004722.2).
SpecificityRecognizes human SLC16A7.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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