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Specifications

Clone Host Grade Applications Polyclonal Sheep Purified E

MCP-1 is a member of the CC subgroup of the chemokine superfamily. It is produced by a variety of cell types including monocytes, lymphocytes, endothelial cells and fibroblasts after stimulation by any inflammatory mediator. MCP-1 acts as a potent chemoattractant and is thought to play an important role in the inflammatory response of blood monocytes, tissue macrophages and natural killer cells. Its expression has been documented in disorders characterized by mononuclear cell infiltrates, suggesting that it may contribute to the inflammatory component of diseases such as atherosclerosis, multiple sclerosis, or rheumatoid arthritis.
Catalog #	M4675-18A
Applications	Suitable for use in ELISA. Other applications not tested.
Recommended Dilution	ELISA: 0.5ug/ml
	Optimal dilutions to be determined by the researcher.
Storage and Stability	May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
CAS Number	n/a
Clone Type	Polyclonal
Isotype	IgG
Host	Sheep
Concentration	~1mg/ml
Form	Supplied as a liquid in 20mM phosphate, 150mM sodium chloride, pH 7.2, 0.09% sodium azide.
Purity	Purified
Immunogen	Recombinant corresponding to aa24-99 from human MCP-1, fused to 6x His-tag expressed in E. coli.
Specificity	Recognizes morphine(6).
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.