You are here:Home
»
Antibodies
»
Abs to Oncoproteins
»
Anti -MOS, CT (Proto-oncogene Serine/threonine-protein Kinase Mos, MGC119962, MGC119963, MSV, Oocyte Maturation Factor Mos, Proto-oncogene c-Mos)
Anti -MOS, CT (Proto-oncogene Serine/threonine-protein Kinase Mos, MGC119962, MGC119963,
MSV, Oocyte Maturation Factor Mos, Proto-oncogene c-Mos)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Purified |
E IH |
|
| Mos, the c-mos protooncogene product, is a key regulator of meiosis in vertebrates. MOS is a 39kDa proto oncogene (c-Mos) encoded protein serine/threonine kinase. MOS is a monomeric protein that indirectly activates MAP kinase (Erk1/2) by directly phosphorylating MAP kinase kinase (Mck, MAPKK, MKK). MOS is known as a cytostatic factor (CSF) and is also thought to arrest unfertilized amphibian and mammalian cells during M phase, thus regulating oocyte maturation. MOS is destroyed before fertilisation, after exit from meiosis II, making it a good marker for studies of eggs during oogenesis and maturation. | | | Catalog # | M4676-02C | | Applications | Suitable for use in ELISA and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | ELISA: 1:1,000 | | Immunohistochemistry: 1:10-1:50 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~0.25mg/ml | | Form | Supplied as a liquid in PBS, 0.09% sodium azide. | | Purity | Purified by ammonium sulfate precipitation. | | Immunogen | Synthetic peptide selected from the C-terminal region of human MOS (KLH). | | Specificity | Recognizes human MOS. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | v-mos Moloney Murine Sarcoma Viral Oncogene Homolog, EC=2.7.11.1 |
External Links
|
