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Specifications

Moxidectin is a semi-synthetic milbemycin derived from nemadectin by selective oxidation followed by methyloximation. Moxidectin was patented in 1991 as an anthelmintic for internal parasite control. The presence of the methyloxime affords moxidectin a greater hydrophobicity and longer biological half-life compared to nemadectin. It binds selectively to parasite
glutamate-gated chloride neurotransmission leading to ion channels and disrupts paralysis and death of the parasite.
Catalog #	M4678-01
Source	Semi-synthetic Moxidectin
Molecular Weight	~639.8
Solubility	Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.
Storage and Stability	Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with DMSO. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
CAS Number	113507-06-5
Molecular Formula	C37H53NO8
Molecular Weight	~639.8
Purity	~95% (HPLC)
Concentration	Not determined
Form	Supplied as a white solid.
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures.