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You are here:Home » Biochemicals » Biochem-Antibiotics » Moxidectin

Moxidectin

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Specifications

Moxidectin is a semi-synthetic milbemycin derived from nemadectin by selective oxidation followed by methyloximation. Moxidectin was patented in 1991 as an anthelmintic for internal parasite control. The presence of the methyloxime affords moxidectin a greater hydrophobicity and longer biological half-life compared to nemadectin. It binds selectively to parasite
glutamate-gated chloride neurotransmission leading to ion channels and disrupts paralysis and death of the parasite.
Catalog #M4678-01
SourceSemi-synthetic Moxidectin
Molecular Weight~639.8
SolubilitySoluble in ethanol, methanol, DMF or DMSO. Limited water solubility.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with DMSO. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
CAS Number113507-06-5
Molecular FormulaC37H53NO8
Molecular Weight~639.8
Purity~95% (HPLC)
ConcentrationNot determined
FormSupplied as a white solid.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures.


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