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You are here:Home » Antibodies » Abs to Multi Drug Resistance (MDR) » Anti -MDR Protein (MRP1, Multidrug resistance-associated protein 1, ABCC1, ATP-binding cassette sub-family C member 1, Leukotriene C(4) transporter)

Anti -MDR Protein (MRP1, Multidrug resistance-associated protein 1, ABCC1, ATP-binding
cassette sub-family C member 1, Leukotriene C(4) transporter)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Ascites B
The MRP molecule, an integral membrane glycophosphoprotein belonging to the same superfamily of ATP-binding cassette transmembrane transporter proteins as P-glycoprotein, is overexpressed in many P-glycoprotein-negative, multidrug resistant cell lines and tumors. It is believed that the main function of MRP in drug resistance is that of a plasma membrane drug efflux pump.
Catalog #M4688-18B
Positive Control 293 transfected lysate
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1
Clone No8L796
HostMouse
SourceHuman
Concentration~6.8mg/ml
FormAs reported
PurityAscites
ImmunogenA recombinant peptide corresponding to residues 1-33 (N-terminal
88% to chicken protein.
87% to bovine protein.
72% to Drosophila melanogaster protein. EpitopeResidues 14-19 (PLWDWN) of the human protein.
SpecificitySpecies Crossreactivity: This antibody crossreacts with human and mouse protein. Other species have not been tested.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesMultidrug Resistance Protein, MRP


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