You are here:Home
»
Antibodies
»
Abs to Multi Drug Resistance (MDR)
»
Anti -MDR Protein (MRP1, Multidrug resistance-associated protein 1, ABCC1, ATP-binding cassette sub-family C member 1, Leukotriene C(4) transporter)
Anti -MDR Protein (MRP1, Multidrug resistance-associated protein 1, ABCC1, ATP-binding
cassette sub-family C member 1, Leukotriene C(4) transporter)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
B IF |
|
| The MRP molecule, an integral membrane glycophosphoprotein belonging to the same superfamily of ATP-binding cassette transmembrane transporter proteins as P-glycoprotein, is overexpressed in many P-glycoprotein-negative, multidrug resistant cell lines and tumors. It is believed that the main function of MRP in drug resistance is that of a plasma membrane drug efflux pump. | | | Catalog # | M4688-18C | | Cellular Localization | Membrane | | Applications | Suitable for use in Immunofluorescence and Western Blot. Other applications not tested. | | Recommended Dilution | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 8L797 | | Host | Mouse | | Source | Human | | Concentration | ~2.08mg/ml | | Form | Supplied as a liquid in Tris-glycine, 150mM sodium chloride, pH 7.2. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | Recombinant peptide (a.a. 1-33) of human MRP1. Epitope: Amino acids 8-17 of human MRP1. | | Specificity | This antibody is specific for MRP1 protein. Species Crossreactivity: This antibody reacts with human and mouse. Other species have not been tested. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | Multidrug Resistance Protein, MRP |
External Links
|
