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You are here:Home » Antibodies » Abs to Multi Drug Resistance (MDR) » Anti -MDR Protein (MRP1, Multidrug resistance-associated protein 1, ABCC1, ATP-binding cassette sub-family C member 1, Leukotriene C(4) transporter)

Anti -MDR Protein (MRP1, Multidrug resistance-associated protein 1, ABCC1, ATP-binding
cassette sub-family C member 1, Leukotriene C(4) transporter)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified B IF
The MRP molecule, an integral membrane glycophosphoprotein belonging to the same superfamily of ATP-binding cassette transmembrane transporter proteins as P-glycoprotein, is overexpressed in many P-glycoprotein-negative, multidrug resistant cell lines and tumors. It is believed that the main function of MRP in drug resistance is that of a plasma membrane drug efflux pump.
Catalog #M4688-18C
Cellular Localization Membrane
ApplicationsSuitable for use in Immunofluorescence and Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1
Clone No8L797
HostMouse
SourceHuman
Concentration~2.08mg/ml
FormSupplied as a liquid in Tris-glycine, 150mM sodium chloride, pH 7.2.
PurityPurified by Protein G affinity chromatography.
ImmunogenRecombinant peptide (a.a. 1-33) of human MRP1. Epitope: Amino acids 8-17 of human MRP1.
SpecificityThis antibody is specific for MRP1 protein. Species Crossreactivity: This antibody reacts with human and mouse. Other species have not been tested.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesMultidrug Resistance Protein, MRP


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