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You are here:Home » Antibodies » Abs to Multi Drug Resistance (MDR) » Anti -MRP2 (Multidrug Resistance-associated Protein 2, ABC30, ATP-binding Cassette Sub-family C Member 2, ATP-binding Cassette Sub-family C (CFTR/MRP) Member 2, ABCC2, Canalicular Multidrug Resistance Protein, CMRP, Canalicular Multispecific Organic Anion Trans

Anti -MRP2 (Multidrug Resistance-associated Protein 2, ABC30, ATP-binding Cassette
Sub-family C Member 2, ATP-binding Cassette Sub-family C (CFTR/MRP) Member 2, ABCC2,
Canalicular Multidrug Resistance Protein, CMRP, Canalicular Multispecific Organic Anion
Trans

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Supernatant B IH IC FC
MRP2 is a 170-180kD transmembrane protein known as the canalicular multi-organic anion transporter, absent in patients with the Dubin-Johnson syndrome, an autosomal recessive liver disorder characterized by chronic conjugated hyperbilirubinemia. MRP2 is closely related to the multidrug resistance related protein MRP, and MRP2 overexpression has been observed in a subset of cisplatin resistant cell lines. Has potential value for detection of MRP2-mediated drug-resistance in human tumor samples.
Catalog #M4688-20B
ApplicationsSuitable for use in Flow Cytometry, Immunocytochemistry, Immunohistochemistry and Western Blot. Other applications not tested.
Recommended DilutionImmunohistochemistry (Acetone fixed frozen): 1:20
Immunocytochemistry: 1:20-1:50 on acetone fixed cytospin preparations.
Western Blot: 1:20-1:50
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone NoM21-4
HostMouse
ConcentrationNot determined
FormSupplied as a liquid, 0.7% BSA, 0.1% sodium azide.
PuritySupernatant
ImmunogenBacterial fusion protein of MRP2 corresponding to aa215-310.
SpecificityRecognizes an internal epitope of human MRP2. Does not cross react with the human MDR1, MRP1, MRP3 and MRP5 gene products.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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