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You are here:Home » Antibodies » Abs to Multi Drug Resistance (MDR) » Anti -MRP8 (ATP-binding Cassette Sub-family C Member 11, Multidrug Resistance-associated Protein 8, ABCC11)

Anti -MRP8 (ATP-binding Cassette Sub-family C Member 11, Multidrug Resistance-associated
Protein 8, ABCC11)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
Participates in physiological processes involving bile acids, conjugated steroids and cyclic nucleotides. Enhances the cellular extrusion of cAMP and cGMP. Stimulates the ATP-dependent uptake of a range of physiological and synthetic lipophilic anions, including the glutathione S-conjugates leukotriene C4 and dinitrophenyl S-glutathione, steroid sulfates such as dehydroepiandrosterone 3-sulfate (DHEAS) and estrone 3-sulfate, glucuronides such as estradiol 17-beta-D-glucuronide (E217betaG), the monoanionic bile acids glycocholate and taurocholate, and methotrexate. Probably functions to secrete earwax.
Catalog #M4688-36D
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:32,000
Western Blot: 0.5-1.5ug/ml, observed in human breast and testis lysates on ~125kD bands
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to C-KVVEFDRPEVLRK, from human ABCC11, at the internal region (near C-terminal) of the protein (NP_115972.2, NP_660187.1).
SpecificityRecognizes human ABCC11. Species sequence homology: Canine and bovine.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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