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Abs to Multi Drug Resistance (MDR)
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Anti -MRP9 (Multidrug Resistance-associated Protein 9, ATP-binding Cassette Sub-family C Member 12, ABCC12, MGC27071)
Anti -MRP9 (Multidrug Resistance-associated Protein 9, ATP-binding Cassette Sub-family C
Member 12, ABCC12, MGC27071)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Rat |
Supernatant |
B IH IC |
|
| Multidrug resistance-associated protein 9 is a protein that in humans is encoded by the ABCC12 gene. This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two ATP-binding domains and 12 transmembrane regions. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White. This gene is a member of the MRP subfamily which is involved in multi-drug resistance. This gene and another subfamily member are arranged head-to-tail on chromosome 16q12.1. Increased expression of this gene is associated with breast cancer. | | | Catalog # | M4688-39 | | Applications | Suitable for use in ELISA, Western Blot, Immunohistochemistry and Immunocytochemistry. Other applications not tested. | | Recommended Dilution | Western Blot: 1:20-1:50 | | Immunohistochemistry (acetone fixed frozen): 1:20-1:50 | | Immunocytochemistry (acetone fixed): 1:20-1:50 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG | | Clone No | M9I-38 | | Host | Rat | | Source | Human | | Concentration | Not determined. | | Form | Supplied as a liquid in 0.7% BSA, 0.1% sodium azide. | | Purity | Supernatant | | Immunogen | Bacterial fusion protein of human MRP9, aa1-42. | | Specificity | Recognizes an internal epitope of human MRP9 (ABCC12) at ~150kD. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | ATP-binding Cassette, Sub-family C (CFTR/MRP), Member 12 |
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