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You are here:Home » Antibodies » Abs to Protein Kinases, Ribosomal » Anti -MSK1, phosphorylated (Thr581) (Mitogen and Stress Activated Protein Kinase 1, MSPK1, 90kD Ribosomal Protein S6 Kinase 5, Nuclear Mitogen And Stress Activated Protein Kinase 1, Ribosomal Protein S6 Kinase 90kD Polypeptide 5, Ribosomal Protein S6 Kinase Alp

Anti -MSK1, phosphorylated (Thr581) (Mitogen and Stress Activated Protein Kinase 1, MSPK1,
90kD Ribosomal Protein S6 Kinase 5, Nuclear Mitogen And Stress Activated Protein Kinase 1,
Ribosomal Protein S6 Kinase 90kD Polypeptide 5, Ribosomal Protein S6 Kinase Alp

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
MSK1, a Mitogen and Stress activated protein Kinase, is activated by ERK as well as p38 MAPK in response to growth factors and various cellular stress stimuli. MSK1 resembles RSK by having two kinase domains connected by a regulator linker region. Phosphorylation of RSK1 at Ser 364, Ser381 and Thr574 is critical for RSK1 activity. These sites are analogous to Ser360, Ser376 and Thr581 of MSK1 and maybe important for MSK1 activity as well.
Catalog #M4692-44B
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 0.5-4ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 1% BSA, 0.02% thimerosal, 50% glycerol.
PurityPurified by affinity chromatography.
ImmunogenSynthetic phosphopeptide surrounding Thr581 from human MSK1.
SpecificityRecognizes human Phospho-MSK1 at ~90kD. Does not cross-react with nonphosphorylated MSK1, MSK1 phosphorylated at other sites, RSK1, RSK2 or RSK3. Species Crossreactivity: mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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