Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Antibodies » Abs to Transcription Factors, Homeobox (HOX) » Anti -Msx1, P5 (Msh Homeobox 1, Msh Homeobox Homolog 1, Msx-1, Homeobox Protein MSX-1, Homeobox Protein MSX1, Homeobox Msh-like 1, HOX-7, HOX7, Hox-7.1, Hox7.1, HYD1, Msh, Msh Homeobox 1-like Protein, Muscle Segment Homeobox, OFC5)

Anti -Msx1, P5 (Msh Homeobox 1, Msh Homeobox Homolog 1, Msx-1, Homeobox Protein MSX-1,
Homeobox Protein MSX1, Homeobox Msh-like 1, HOX-7, HOX7, Hox-7.1, Hox7.1, HYD1, Msh, Msh
Homeobox 1-like Protein, Muscle Segment Homeobox, OFC5)

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
Msh homeobox 1 (Msx1) is a Muscle Segment Homeobox (Msh) gene family member that acts as a transcriptional repressor during embryonic development, playing an important role in limb pattern formation, cranio-facial development, and tooth development (1-3). Msx1 is
expressed in the mesenchyme of the developing nail bed (2) and in fetal hair follicles, epidermis and fibroblasts; reduced expression is seen in adult epithelial-derived tissues (4).
Msx1 acts in concert with the Wnt1 network to establish the midbrain dopaminergic progenator domain, a region that gives rise to neurons that are critical for normal brain function and are the cells affected in Parkinson disease (5). Mutation in the corresponding Msx1 gene correlates with
abnormal tooth development in patients diagnosed with Wolf-Hirschhorn syndrome (6). Other genetic changes in the Msx1 gene result in Witkop Syndrome (“tooth and nail syndrome”) and cases of abnormal tooth development as-sociated with non-syndromic orofacial clefting (2,7).
Catalog #M4692-74D
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1:1000 Incubate membrane with diluted antibody in 5% w/v BSA, 1X TBS, 0.1% Tween-20 at 4°C with gentle shaking, overnight.
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in 10mM sodium HEPES pH 7.5, 0.1%, 150mM NaCl, 100ug/ml BSA and 50% glycerol.
PurityPurified by Protein A affinity chromatography.
ImmunogenSynthetic peptide corresponding to amino acid sequences surrounding Pro5 of human Msx1 protein (KLH-coupled).
SpecificityRecongnizes endogenous levels of human total Msx1 protein. Sequence Homology: monkey.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


External Links