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You are here:Home » Biochemicals » Biochem-Antibiotics » MS-275 (Entinostat, SNDX-275)

MS-275 (Entinostat, SNDX-275)


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Preferentially inhibits HDAC1 (IC50=300 nM) over HDAC3 (IC50=8uM). Has no inhibitory activity towards HDAC8 (IC50>100uM).
Catalog #M4693-15
ApplicationsSuitable for use as a histone deacetylase inhibitor. Other applications have not been tested
Recommended Dilutions
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Reconstitute with DMSO. Aliquot and store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
CAS Number209783-80-2
Molecular FormulaC21H20N4O3
Molecular Weight376.41
FormSupplied as a solid. Reconstitute with DMSO.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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