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You are here:Home » Antibodies » Abs to Mucin » Anti -MUC1, phosphorylated (Tyr1203) (Mucin-1, MUC-1, Polymorphic Epithelial Mucin, PEM, PEMT, Episialin, Tumor-associated Mucin, Carcinoma-associated Mucin, Tumor-associated Epithelial Membrane Antigen, EMA, H23AG, Peanut-reactive Urinary Mucin, PUM, Breast Ca

Anti -MUC1, phosphorylated (Tyr1203) (Mucin-1, MUC-1, Polymorphic Epithelial Mucin, PEM,
PEMT, Episialin, Tumor-associated Mucin, Carcinoma-associated Mucin, Tumor-associated
Epithelial Membrane Antigen, EMA, H23AG, Peanut-reactive Urinary Mucin, PUM, Breast Ca

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E Gel
MUC1 is a member of the mucin family and a membrane bound, glycosylated phosphoprotein. The protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It also includes a 20 aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 20 to 120 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas.
Catalog #M4700-09A
ApplicationsSuitable for use in ELISA and Dot Blot. Other applications not tested.
Recommended DilutionELISA: 1:1,000
Dot Blot: 1:500
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
CAS Numbern/a
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~0.25mg/ml
FormSupplied as a liquid in PBS, 0.09% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenSynthetic phosphopeptide corresponding to amino acid residues surrounding Tyr1203 of human MUC1 (KLH).
SpecificityRecognizes human MUC1 when phosphorylated at Tyr1203..
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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