Anti -MUC1, phosphorylated (Tyr1203) (Mucin-1, MUC-1, Polymorphic Epithelial Mucin, PEM, PEMT, Episialin, Tumor-associated Mucin, Carcinoma-associated Mucin, Tumor-associated Epithelial Membrane Antigen, EMA, H23AG, Peanut-reactive Urinary Mucin, PUM, Breast Ca
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
E Gel |
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| MUC1 is a member of the mucin family and a membrane bound, glycosylated phosphoprotein. The protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It also includes a 20 aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 20 to 120 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. | | | Catalog # | M4700-09A | | Applications | Suitable for use in ELISA and Dot Blot. Other applications not tested. | | Recommended Dilution | ELISA: 1:1,000 | | Dot Blot: 1:500 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~0.25mg/ml | | Form | Supplied as a liquid in PBS, 0.09% sodium azide. | | Purity | Purified by Protein A affinity chromatography. | | Immunogen | Synthetic phosphopeptide corresponding to amino acid residues surrounding Tyr1203 of human MUC1 (KLH). | | Specificity | Recognizes human MUC1 when phosphorylated at Tyr1203.. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -MUC1, phosphorylated (Tyr1203) (Mucin-1, MUC-1, Polymorphic Epithelial Mucin, PEM, PEMT, Episialin, Tumor-associated Mucin, Carcinoma-associated Mucin, Tumor-associated Epithelial Membrane Antigen, EMA, H23AG, Peanut-reactive Urinary Mucin, PUM, Breast Ca |
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