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Anti -Mucin 1 (MUC1 Glycoprotein, CD227)
Anti -Mucin 1 (MUC1 Glycoprotein, CD227)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
B IH |
|
| Mucins are heavily glycosylated glycoproteins, which constitute the major components of mucus which cover the surface of epithelial tissues. Nine distinct epithelial mucin genes (Muc-1, 2, 3, 4, 5AC, 5B, 6, 7 and 8) have been identified. Various immunohistochemical and in situ hybridization studies have shown that these mucins are differentially expressed in epithelia with cell-type specificity. Muc-5AC and Muc-6 glycoproteins are the first two mucins found in superficial epithelium and Muc-6 glycoprotein is found in the deep glands. Belongs to monoclonal cluster 1-4 according to ISOMB TD-4 classification. | | | Catalog # | M4700-11C | | Applications | Suitable for use in Western Blot and Immunohistochemistry. Other applications have not been tested. | | Recommended Dilution | Immunohistochemistry: Frozen tissue sections or formalin fixed paraffin wax embedded tissue sections. | | Note: HIER (Microwave, citrate buffer pH 6.0) may be advantageous for some applications. | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 2Q441 | | Host | Mouse | | Source | Human | | Concentration | ~0.1mg/ml | | Form | Supplied as a liquid in PBS, 1mg/ml BSA, 10mM sodium azide. | | Purity | Purified by Protein A affinity chromatography | | Immunogen | Human breast cancer cell line ZR-75-1. | | Specificity | Recognizes the extracellular human 12-mer GVTSAPDTRPAP epitope of the MUC-1 tandem repeat. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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