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You are here:Home » Antibodies » Abs to Mucin » Anti -Mucin 1 (MUC1 Glycoprotein, CD227)

Anti -Mucin 1 (MUC1 Glycoprotein, CD227)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified B IH
Mucins are heavily glycosylated glycoproteins, which constitute the major components of mucus which cover the surface of epithelial tissues. Nine distinct epithelial mucin genes (Muc-1, 2, 3, 4, 5AC, 5B, 6, 7 and 8) have been identified. Various immunohistochemical and in situ hybridization studies have shown that these mucins are differentially expressed in epithelia with cell-type specificity. Muc-5AC and Muc-6 glycoproteins are the first two mucins found in superficial epithelium and Muc-6 glycoprotein is found in the deep glands. Belongs to monoclonal cluster 1-4 according to ISOMB TD-4 classification.
Catalog #M4700-11C
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications have not been tested.
Recommended DilutionImmunohistochemistry: Frozen tissue sections or formalin fixed paraffin wax embedded tissue sections.
Note: HIER (Microwave, citrate buffer pH 6.0) may be advantageous for some applications.
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone No2Q441
HostMouse
SourceHuman
Concentration~0.1mg/ml
FormSupplied as a liquid in PBS, 1mg/ml BSA, 10mM sodium azide.
PurityPurified by Protein A affinity chromatography
ImmunogenHuman breast cancer cell line ZR-75-1.
SpecificityRecognizes the extracellular human 12-mer GVTSAPDTRPAP epitope of the MUC-1 tandem repeat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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