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You are here:Home » Antibodies » Abs to Mucin » Anti -MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Carcinoma-associated Mucin, Episialin, H23AG, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-associated Epithelial Membrane Antigen, EMA, Tumor-associated M

Anti -MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Carcinoma-associated
Mucin, Episialin, H23AG, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial
Mucin, PEM, Tumor-associated Epithelial Membrane Antigen, EMA, Tumor-associated M

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IP IH
Muc-1 is a heavily O-glycosylated transmembrane protein expressed on most secretory epithelium, including mammary gland and some hematopoietic cells. It is expressed abundantly in lactating mammary glands and overexpressed abundantly in >90% breast carcinomas and metastases. Transgenic Muc-1 has been shown to associate with all four cebB receptors and localize with erbB1 (EGFR) in lactating glands.
Catalog #M4700-12B
ApplicationsSuitable for use in Immunoprecipitation, Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry: 1:100 for 10min at RT
Optimal dilutions to be determined by the researcher.
Positive ControlMCF-7 cells, breast carcinoma
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostRabbit
SourceHuman
Concentration~0.1mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 0.2% BSA, 0.05% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to the cytoplasmic tail of human MUC1.
SpecificityRecognizes human MUC1. Species Crossreactivity: mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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