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You are here:Home » Antibodies » Abs to Mucin » Anti -Mucin 2 (MUC2 Glycoprotein) (FITC)

Anti -Mucin 2 (MUC2 Glycoprotein) (FITC)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified FC
MUC-type mucins comprise a family of structurally related high molecular weight (> 200kD) glycoproteins that are expressed in different epithelia that are in close contact with the milieu. Because of their large size and very complex structure, containing very extensive O-glycosylation, MUC-type mucins are difficult to study by conventional techniques. Mucins are seen as protective molecules. However, functional studies are scarce. MUC2 is an intestinal apomucin also known as intestinal MRP (Mucin Related Protein) antigen. It is expressed in mucinous tumors but not in serous tumors. Expression of MUC-2 is found in a low percentage of borderline malignancies and in ~55% of carcinomas that also express MUC1.
Catalog #M4700-24A
ApplicationsSuitable for use in Flow Cytometry. Other applications not tested.
Recommended DilutionsFlow Cytometry: Neat-1:10; Use 10ul to label 1x10e6 cells in 100ul. Membrane permeabilization is required.
Optimal dilutions to be determined by the researcher.
SourceTissue culture supernatant
HybridomaNSO myeloma cells with spleen cells from Balb/c mice.
Recommended Negative ControlI1904-78R3: IgG1 Murine Negative Control (FITC)
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. FITC conjugates are sensitive to light.
Clone TypeMonoclonal
IsotypeIgG1
Clone No9E45
HostMouse
SourceHuman
Concentration~0.1mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 1% BSA, 0.09% sodium azide. Labeled with fluorescein isothiocyanate (FITC).
PurityPurified by Protein G affinity chromatography.
ImmunogenMUC2 tandem repeat peptide
SpecificityRecognizes human Mucin 2 (MUC2). Does not crossreact with MUC1, MUC3 or MUC4 mucins.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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