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You are here:Home » Antibodies » Abs to Mucin » Anti -MUC2 (Mucin-2, MUC-2, Intestinal Mucin-2, SMUC)

Anti -MUC2 (Mucin-2, MUC-2, Intestinal Mucin-2, SMUC)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified B IH
MUC-type mucins comprise a family of structurally related high molecular weight (>200kD) glycoproteins that are expressed in different epithelia that are in close contact with the milieu. Because of their large size and very complex structure, containing very extensive O-glycosylation, MUC-type mucins are difficult to study by conventional techniques. Mucins are seen as protective molecules; however, functional studies are scarce. MUC2 is an intestinal apomucin also known as intestinal MRP (Mucin Related Protein) antigen. It is expressed in mucinous tumors but not in serous tumors. Expression of MUC-2 is found in a low percentage of borderline malignancies and in ~55% of carcinomas that also express MUC1.
Catalog #M4700-24B
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml
Immunohistochemistry: Frozen
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone No996/1
HostMouse
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH7.4, 0.09% sodium azide.
PurityPurified by Protein G affinity chromatography.
ImmunogenSynthetic peptide corresponding to human MUC2.
SpecificityRecognizes human MUC2.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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