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You are here:Home » Biochemicals » Biochem-Antibiotics » Monensin A

Monensin A

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Specifications

Monensin A is a polyether antibiotic first isolated from Streptomyces cinnamonensis in 1967. Monensin is a broad- spectrum anticoccicidial antibiotic also exhibiting antifungal and antiviral activity. Monensin A forms complexes with monovalent cations such as Li+, Na+, K+, Rb+, Ag+ and Tl+ and is thus able to transport these cations across lipid membranes of cells, playing an important role as an Na+/H+ antiporter. It blocks intracellular protein transport and is used in the treatment of animals to prevent coccidiosis, promote growth and prevent bloat. Derivatives of monensin, monensin methyl ester and particularly monensin decyl ester, are used in ion selective electrodes.
Catalog #M4900-01
SourceMonensin A from Streptomyces sp.
Molecular Weight~670.8
SolubilitySoluble in ethanol, methanol, DMF or DMSO. Limited water solubility.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with DMSO. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
CAS Number17090-79-8
Molecular FormulaC36H62O11
Molecular Weight~670.8
Purity~95% (HPLC)
ConcentrationNot determined
FormSupplied as a white solid.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures.


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