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You are here:Home » Antibodies » Abs to Receptors, Cholinergic » Anti -Muscarinic Receptor M1 (Cholinergic Muscarinic Receptor M1, Cholinergic Receptor Muscarinic 1, Chrm1, CHRM-1, HM1, M1, M1 Muscarinic Cholinergic Receptor, MGC30125, Muscarinic Acetylcholine Receptor M1)

Anti -Muscarinic Receptor M1 (Cholinergic Muscarinic Receptor M1, Cholinergic Receptor
Muscarinic 1, Chrm1, CHRM-1, HM1, M1, M1 Muscarinic Cholinergic Receptor, MGC30125,
Muscarinic Acetylcholine Receptor M1)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13.
Catalog #M9520-03D
Positive Control Human Brain lysate
ApplicationsSuitable for use in ELISA (peptide) and Western Blot. Other applications not tested.
Recommended DilutionELISA (peptide): 1:16,000
Western Blot: 1-3ug/ml. ~ 48kD band observed in Human Brain lysates (calculated MW of 51.4kD according to NP_000729.2).
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris-saline, pH7.2, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide, CDKRRWRKIPKRPGSVH, representing the C Terminus of the human protein according to NP_000729.2. Homology: Human, Mouse, Rat, Dog
SpecificitySpecies Crossreactivity: Human. Other species not tested.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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