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You are here:Home » Antibodies » Abs to Receptors, Cholinergic » Anti -Muscarinic Acetylcholine Receptor M2 (Chrm2, CHRM-2, 7TM Receptor, FLJ43243, HM2, MGC120006, MGC120007)

Anti -Muscarinic Acetylcholine Receptor M2 (Chrm2, CHRM-2, 7TM Receptor, FLJ43243, HM2,
MGC120006, MGC120007)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified IH
M2 (CHRM2) is a 60kD 7-transmembrane glycoprotein that is predominantly expressed in the heart and central nervous system. CHRM2 mediates signal transduction in the autonomic nervous system in response to muscarinic agonists. Polymorphisms of CHRM2 are associated with alcohol dependence, depression, bipolar disorder, and recovery of heart function after myocardial infarction. Human CHRM2 shares 96% aa sequence identity with mouse and rat CHRM2.
Catalog #M9520-14F
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry: 25ug/ml
Optimal dilutions to be determined by the researcher.
HybridomaMyeloma cells with B cells from Balb/c mice.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG2b
Clone No11D3
HostMouse
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a lyophilized powder from PBS, 5% trehalose. Reconstitute with 200ul sterile PBS.
PurityPurified by Protein G affinity chromatography.
ImmunogenRecombinant corresponding to human CHRM2 expressed in NSO cells (P08172).
SpecificityRecognizes human CHRM2.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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