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You are here:Home » Antibodies » Abs to Receptors, Cholinergic » Anti -Muscarinic Receptor M3 (Cholinergic Muscarinic Receptor M3, Cholinergic Receptor Muscarinic 3, Chrm3, HM3, M3 Muscarinic Receptor, Muscarinic Acetylcholine Receptor M3, Muscarinic 3)

Anti -Muscarinic Receptor M3 (Cholinergic Muscarinic Receptor M3, Cholinergic Receptor
Muscarinic 3, Chrm3, HM3, M3 Muscarinic Receptor, Muscarinic Acetylcholine Receptor M3,
Muscarinic 3)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified IH
Muscarinic receptor M3 is a G protein-coupled receptor for acetylcholine which is expressed in smooth muscle and glandular tissues. The M3 subtype is coupled to other G proteins known as Go or Gq which activate phospholipase C leading to an increase in intracellular Ca2+. The M3 muscarinic receptor controls smooth muscle contraction in blood vessels and lungs as well as in the gastrointestinal tract. It is also located in many glands, and its activation helps to stimulate secretion.
Catalog #M9520-21K
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (paraffin): 10ug/ml
Requires antigen retrieval using heat treatment for 20 minutes prior to staining of paraffin sections. 0.01M sodium citrate buffer, pH 6.0 is recommended for this purpose.
Optimal dilutions to be determined by the researcher.
Histology Positive Control Tissue Brain, cortex.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, pH 7.7, 0.09% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to the 3rd cytoplasmic domain of human muscarinic receptor M3 (KLH).
SpecificityRecognizes human muscarinic receptor M3. Species sequence homology: mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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