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You are here:Home » Antibodies » Abs to Receptors, Cholinergic » Anti -Muscarinic Receptor M3 (Muscarinic Acetylcholine Receptor M3, Cholinergic Receptor Muscarinic 3, CHRM3, HM3)

Anti -Muscarinic Receptor M3 (Muscarinic Acetylcholine Receptor M3, Cholinergic Receptor
Muscarinic 3, CHRM3, HM3)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified IH
Muscarinic acetylcholine receptor 3 is an Acetylcholine Receptor that controls smooth muscle contraction by mediating phosphoinositide hydrolysis and Ca2+ mobilization. Activation of this receptor causes secretion in glandular tissues. mouse studies suggest that the M3 receptor may play a role in appetite stimulation and food intake. Expression of this receptor has been reported in brain, eye, and heart. ESTs have been isolated from brain, colon, fetus, lung, and prostate libraries.
Catalog #M9520-21R
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (paraffin): 72ug/ml
Optimal dilutions to be determined by the researcher.
Positive ControlHuman Brain, Neurons and glia
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.7, 0.01% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to the 3rd cytoplasmic domain of human Muscarinic Acetylcholine Receptor M3.
SpecificityRecognizes human mAChR M3.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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