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You are here:Home » Antibodies » Abs to Receptors, Cholinergic » Anti -Muscarinic Receptor M4 (Muscarinic Acetylcholine Receptor M4, Cholinergic Receptor Muscarinic 4, CHRM4, HM4, M4R)

Anti -Muscarinic Receptor M4 (Muscarinic Acetylcholine Receptor M4, Cholinergic Receptor
Muscarinic 4, CHRM4, HM4, M4R)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified IH
Muscarinic acetylcholine receptor M4 is an Acetylcholine Receptor. Unlike muscarinic receptor M2, the M4 receptor is not involved in smooth muscle contraction. The clinical relevance of this receptor is unknown. However, mouse studies have linked it to adenylyl cyclase inhibition. Muscarinic acetylcholine receptor M4 has been reported to be expressed in many regions of the rat brain, particularly the striatum and hippocampus. ESTs have been isolated from Human breast and eye libraries.
Catalog #M9520-31G
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (paraffin): 9ug/ml
Optimal dilutions to be determined by the researcher.
Positive ControlHuman brain, purkinje neurons
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.7, 0.01% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to the 3rd cytoplasmic domain of human mAChR M4.
SpecificityRecognizes human mAChR M4.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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