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You are here:Home » Antibodies » Antibodies-Cell Markers » Anti -MYADM (Myeloid-associated Differentiation Marker, Protein SB135, UNQ553/PRO1110)

Anti -MYADM (Myeloid-associated Differentiation Marker, Protein SB135, UNQ553/PRO1110)


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Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IH
MYADM, belonging to the MAL family, is a 322aa protein having 7 hydrophobic transmembrane domains, several potential consensus sites for phosphorylation and sequence homology with the T-cell differentiation protein MAL and plasmolipin. It shares 75.8% sequence identity with mouse in the transmembrane regions and is associated with differentiation of hematopoietic cells or acute promyelocytic leukemia cells. Its expression is up-regulated in NB4 cells induced by all-trans retinoic acid whereas down regulation inhibits colony formation of bone marrow cells. MYADM could serve as a new marker for hematopoietic differentiation and is a target for diagnostic, prognostic and/or therapeutic interventions. It is known to express widely in brain and pancreatic islet cells.
Catalog #M9599-05
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 0.2-1ug/ml
Immunohistochemistry (formalin fixed paraffin embedded): 1.25-10ug/ml
Optimal dilutions to be determined by the researcher.
Positive ControlHuman spleen lysate
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
FormSupplied as a liquid in PBS, 0.2% gelatin, 0.05% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to aa250-300 of human MYADM.
SpecificityRecognizes human MYADM. Species Crossreactivity
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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