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You are here:Home » Antibodies » Abs to Myelin » Anti -Myelin Basic Protein (MBP)

Anti -Myelin Basic Protein (MBP)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Purified E IH
Myelin basic protein accounts for about 30% of the proteins in myelin from the central nervous system. It is best known for its capacity to induce experimental allergic encephalomyelitis (EAE), a T-lymphocyte mediated disease due to delayed-type hypersensitivity; though each animal species appears to respond to a different fragment of the 170 amino acid polypeptide. Myelin basic protein is expressed in oligodendrocytes, myelin of white matter in the brain and spinal cord and in peripheral nerves.
Catalog #M9758-02L
ApplicationsImmunohistology (Formalin/paraffin): (Use Ab at 1:50 to 1:100 for 30 min at RT) No special pretreatment is required for the immunohistochemical staining of formalin/paraffin tissues.
Positive Control Brain
Cellular Localization Cytoplasmic
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Store at -20°C or colder. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in 10mM PBS, pH 7.4, 0.2% BSA and 0.09% sodium azide.
PurityPurified antibody fraction from rabbit anti-serum.
ImmunogenMyelin basic protein isolated from human brain.
SpecificityRecognizes Myelin Basic Protein. Species Crossreactivity: Human.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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