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Specifications

Clone Host Grade Applications Monoclonal Mouse Ascites IH IC

This protein is found exclusively on oligodendrocytes and myelin in the central nervous system (CNS). Myelin is produced by oligodendrocytes in the CNS and Schwann cells in the peripheral nervous system (PNS). Defining the differences between CNS and PNS myelin may provide insights into the process of myelination and the pathogenesis of certain idiopathic diseases involving myelin such as multiple sclerosis, certain leukodystrophies, and other myelinopathies. On de-myelination, immunoreactivity for MOSP, like MBP, is lost.
Catalog #	M9758-07A
Applications	Suitable for use in Immunocytochemistry and Immunohistochemistry. Not recommened for use in Western Blot. Other applications have not been tested.
Recommended Dilutions	Immunohistochemistry: 1:1000-1:5000
	Optimal dilution determined by the researcher.
Storage and Stability	May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
CAS Number	n/a
Clone Type	Monoclonal
Isotype	IgM
Clone No	2Q91
Host	Mouse
Source	Rat
Concentration	Not Determined
Form	Supplied as a liquid in PBS. No preservatives added.
Purity	Ascites
Immunogen	Rat glial membranes and whole brain white matter.
Specificity	Recognizes rat Myelin and Oligodendrocytes. Stains oligodendrocytes in neonatal rat glia. Does not crossreact with type 1 astrocytes, type 2 astrocytes or fibroblasts. Does not stain cultures of rat Schwann cells. Does not label peripheral myelin. Labels oligodendrocytes and CNS myelin in tissue sections. Species Crossreactivity: human, chick, mouse, ferret, feline and monkey.
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.